3D geometric model of the flow in material inlet and outlet and three-way valve was established using Pro/E according to the structure and parameters of the piston filling machine for high viscous materials. The meshes of the model were fractionized by the preprocessor Gambit and then calculated in Fluent. The movement between the filling valve and the piston, the flow rate and pressure of different position the spool, and the turbulence intensity of high viscous materials were analyzed using CFD. The relationship among turbulence intensity, velocity, discharge coefficient, flow, and angel was obtained. The purpose was to provide reference for design and optimization of high viscosity material filling.