Current MAP equipment has the deficiencies of low replacement rate caused by compensation style, low gas mixing precision caused by pressure regulation, low efficiency caused by half automation, not enough cooling and sterilization, and secondary pollution. Fully automatic MAP equipment with the functions of pre-cooling, sterilization, and modified atmosphere was designed to solve the above deficiencies. Besides, two pre-cooling system modes were designed for different packaging boxes and products requirements, which were semiconductor refrigeration technology applicable to small cold quantity packaging products and refrigeration compressor vacuum pre-cooling system applied in larger cold quantity. Refrigeration mode selection and theoretical calculation and analysis methods were also introduced.