The main content of CLP regulation announced by European Union on December 16, 2008 was analyzed. The purpose, scope, and execution time of using CLP regulation were introduced. The substances and compounds’ classification methods, labeling elements and special packaging requirements in CLP regulation were described. The management of chemical in USA, Japan, EU, and our country was analyzed. Potential impacts of CLP regulation on packaging industry was analyzed with view of development, such as the improvement of packaging requirements of export products and indirect increase on import products cost. Suggestions were put forward for China packaging industry to deal with the CLP regulation.