The existing problems of present dangerous transport cases were studied. UHMWPE-PUF composite material was prepared in laminated composite technology. A new dangerous transport case was developed by using UHMWPE/PUF composite material and explosive destructive experiment was carried out. The results showed that UHMWPE-PUF composite material can improve maximally not only the strength but also shock wave attenuation properties of the material; the weight of new dangerous transport case was reduced with improved anti-detonation ability.