Based on the analysis of two uniformity detection models stated by ISO13660, a new model which took human visual system into consideration was introduced. These models were used to detect the uniformity of print acquired by CCD device through experiment, and their consistent with human visual evaluation was compared. The results showed that IM Mottle model considering human vision can reflect the uniformity of print better; mottle stated by ISO13660 has greater impact on the uniformity of print than graininess.