Size and stability of droplet directly influence the quality of ink-jet imaging, so analysis and research on droplet ejection of ink-jet printing is very necessary. Ethylene glycol droplet ejection experiment was carried out using a set of piezoelectric ink-jet printing device. The influence of operating frequency, pulse time, pulse voltage, pulse shape and other experimental parameters on droplet ejection effect was studied. The experiments showed that changing different parameters will affect the droplet formation mechanism. Each of parameters was observed separately, in order to find the best conditions for droplet ejection.