Application of QFD in packaging design process was proposed to improve the design quality of packaging products and shorten the design cycle. Basic flow of applying QFD in packaging design was analyzed in details, namely, quality requirements of customers on package products were taken as reference; typical methods of system analysis were combined to construct two stage HOQ of product planning and part planning; and key quality control points during packaging product process were finally output. Examples of packaging design were analyzed on the basis. The results showed that products meeting market demands can be designed more quickly and accurately by the aid of QFD application in packaging design.