Wood adhesives were prepared by crosslink and graft modification method with starch as raw materials, epichlorohydrin and ethyl-acrylate as chemical modifying agents respectively. Experiment results showed that the proper amount of epichlorohydrin was 4.0 wt%, and 60% starch should be put into reactor at starting and another 40% at interval of 2 h in the process of cross-linking. The optimum graft conditions determined by orthogonal design were as follows: ammonium persulfate 0.2wt%, ethyl-acrylate 10.0 wt%, reaction time 3h, reaction temperature 70 ℃. The wood adhesives has high bond strength（7.5 MPa）, good water-resistance（48 h）, stable storage stability（200 d）, which can meet the requirement of national standard GB/T 9846-2004.