The work aims to take the NEWTOP high-speed intelligent paper cup forming machine as the research object to analyze the working principle of the curling and sealing mechanism of the paper cup forming machine and carry out optimized design and simulation analysis of its structure, so as to design an efficient and precise curling and sealing mechanism. Through the theoretical design and analysis of the cam of the curling and sealing transmission mechanism, an optimized design scheme was put forward for the cam. Moreover, a three-dimensional solid model was established by the SOLIDWORKS software, and the kinematic simulation software ADAMS was applied to conduct simulation analysis of the cam mechanism. The displacement, speed and acceleration curves of the cam mechanism indicated that the mechanism underwent variable-speed motion, and the acceleration curve tended to follow the law of sinusoidal acceleration motion, which was suitable for cams that rotated at high speed. The research has solved the problems such as the low working efficiency and short service life of the existing curling and sealing mechanism, and has improved the efficiency of the paper cup forming machine.