The work aims to analyze the quality and safety risks brought by the coding technology applied on milk powder peel-off ends through analyzing and testing the quality and food safety of coded milk powder peel-off ends. Surface friction tests, corrosion resistance tests, food safety compliance tests, and untargeted screening analyses were conducted on coded milk powder peel-off ends to evaluate the quality performance and food safety test results. The results showed that no black or gray substances were found after the surface friction tests, and a certain level of corrosion resistance was found on the coded area. In addition, according to the results of the food safety compliance tests, coded milk powder peel-off ends fulfilled the corresponding international requirements. Through the untargeted screening analyses, it was found that food safety risks would not be brought by coded peel-off ends. The risks brought by the coding technology applied on milk powder peel-off ends are low. Therefore, coded peel-off ends could be used on milk powder packaging.