In order to realize the pattern of quantum dot films by inkjet printing technology, the work aims to adjust the parameters of the preparation process of quantum dot films to obtain the films with uniform surface, suitable thickness and no coffee ring structure. Substrate and annealing were two important parameters that affected the film forming performance of quantum dot films. The effects of substrate cleaning, material and temperature, and annealing temperature and time on the film forming performance of inkjet printing quantum dot films were studied respectively. Three different types of solvents were chosen to clean the substrate in sequence, improving the surface energy of substrate, which was conducive to the spread of ink. Compared with Pedot:Pss, the film morphology of quantum dot surface on PVK substrate was more uniform. When the substrate temperature was 50 ℃, the annealing temperature was 80 ℃ or 90 ℃, and the annealing time was 15 minutes, the coffee ring effect was the weakest, and the quantum-dot films with uniform surface, suitable thickness and no coffee ring structure were obtained. The cleaning of the substrate, its own material and temperature will affect the spreading performance of the ink, and thus affect the forming performance of the quantum dot film. Annealing temperature and annealing time are controlled to make the the Marangoni Stream work, the coffee ring effect is suppressed obviously, and the uniform surface of quantum dot films can be obtained.