The work aims to establish a static and dynamic model with a cylindrical air cushion packaging system as the research object, to study the characteristics of static compression, free vibration and forced vibration under foundation excitation. A mathematical model for the compression force of the air cushion was established and verified through experiments and simulations. By establishing a mechanical model of a pre-compression cylindrical air cushion packaging system, the static and dynamic characteristics were studied. The dynamic analysis of the packaging system showed that the higher the pre-compression and inflation pressure, the higher the natural frequency of the packaging system. Under the constraint of the fixed width of the packaging object, selecting multiple small diameter air cushion resulted in higher natural frequencies and lower Von-mises stress. Under the foundation excitation, there was a resonance peak at the natural frequency of the packaging system, which showed a good vibration reduction characteristics for air cushion in the high frequency domain. The static compression model established is in good agreement with the experimental and simulation results. The dynamic model established is reasonable and accurate.