In order to ensure transportation safety, wheeled goods need to be limited by wheel chocks during railway transportation. In response to the current situation and existing problems in railway transportation of wheeled goods in China, the work aims to propose a concept of collaborative design between vehicle body and reinforcement device, and design an adjustable wheel chock, which is suitable for wheeled goods of various wheel diameters, with integrated storage and use, high reliability, and fast use. SolidWorks was used to establish a three-dimensional model of wheel chocks. The strength of railway transportation reinforcement was calculated. The strength requirements for wheel chocks under the most unfavorable conditions were determined. Load and constraint analysis were conducted. Finite element analysis software SolidWorks simulation was used for simulation calculation and strength analysis. The stress and displacement of the wheel chock under the most unfavorable working conditions were obtained. The maximum stress occurred at the connection between the bottom surface of the wheel chock and the movable pin, with a maximum stress value of 499.9 MPa, which did not exceed the allowable stress of the material used in the design (585 MPa); The maximum displacement was 0.99 mm, which was within the allowable range. In conclusion, the strength of the wheel chocks meets the requirements for safe transportation, and can be used for loading and reinforcement of various wheeled goods in railway transportation, effectively improving reinforcement efficiency.