The work aims to provide an overview of the research on the application of micro-nano processing technologies in packaging anti-counterfeiting to help practitioners in related industries to understand more clearly and comprehensively the current development and application status of micro-nano processing technologies in packaging anti-counterfeiting, and promote their promotion and application in this field. In this work, relevant research was divided into three aspects, namely, the application research of micro-nano processing technology in the preparation of new anti-counterfeit labels, the preparation of new anti-counterfeit materials and digital anti-counterfeiting field. Relevant research profiles, key scientific and technological implementation methods and core anti-counterfeiting mechanisms were sorted out. Advantages, disadvantages and the development trend of micro-nano processing technologies in packaging anti-counterfeiting were analyzed. Challenges and future development directions of composite anti-counterfeiting technologies were highlighted. This research shows that the rapid development of micro-nano processing technologies provides a new tool and technology for anti-counterfeiting technology. The composite anti-counterfeiting technology composed of micro-nano processing technology and information technology, etc. has shown great potential for commercial application. However, the application of micro-nano processing technologies in packaging anti-counterfeiting is still in the initial stage, and most of the laboratory results are still limited by cost and reliability when facing industrialization. How to further reduce the cost of equipment and materials and optimize the process flow while meeting the accuracy requirements in the future requires more in-depth exploration and research.