The work aims to improve the shortcomings of soybean protein glue, such as easy mildew, short storage time and low performance of the board prepared with soybean protein adhesive, so as to extend the service life of plywood and broaden the application scope and field of the board. The reason why soybean protein glue and plywood were easy to mildew and the research progress in recent years in China and abroad on the mildew resistance of soybean protein glue and plywood were summarized, the modification principle and existing problems were analyzed, and the current application of atom transfer radical polymerization (ATRP) in the modification of soybean glue was introduced. The anti-mildew grafting modification of soybean protein adhesive by ATRP method can prolong the service life of plywood while ensuring the bonding strength, which provides a new idea for the preparation of soybean protein plywood with excellent mildew resistance and industrial popularization in the future.