The work aims to establish a theoretical model for the relationship between ink dynamic pressure and printing parameters, and a finite element model for the relationship between ink dynamic pressure and ink flow rate, so as to study the effect of screen printing parameters on ink flow rate. The relationship between screen printing parameters and ink dynamic pressure was studied with the knowledge of fluid mechanics. The relationship curve between ink dynamic pressure and ink flow rate was constructed by the finite element method. Finally, the simulation results were verified by design experiments. The curve of mesh ink flow rate and wedge dynamic pressure showed that mesh ink flow rate was positively correlated with wedge dynamic pressure, and the error between simulation and experiment results was within 10%. The simulation results of screen printing are basically consistent with the printing experimental results, and the relationship between the printing parameters and ink flow rate can better estimate the impact of printing parameters on ink flow rate, providing theoretical guidance for achieving ink flow rate control.