The work aims to design a safe and efficient packaging process for chromic anhydride material drums to address the corrosive and toxic nature of chromic anhydride, as well as the safety hazards it poses to human health in the manual packaging environment. An automatic packaging system based on three-coordinate truss was proposed, in which the mechanical arm automatically grabbed the drum cover to complete the automatic charging process of the drum cover, the screw and nut feeder completed the sequence feeding process of the screw and nut by gravity effect, and the bolt capping mechanism completed the bolting of the material drum cover, so as to realize automatic packaging of the three-coordinate quilted packaging system. The rationality of the packaging technology was verified by digital simulation and experiment. In the packaging, the bolt capping mechanism of precision design realized automatic supply and high load accurate bolt packaging process. The designed automated encapsulation system achieved a packaging speed of up to 1.2 units per minute, with a 100% success rate during the experimental phase. The equipment structure is reasonable. Under the premise of ensuring the quality of chromic anhydride material packaging, it reasonably avoids the safety risks caused by artificial production, promotes the process of automation in chemical enterprises, and provides a solution for automatic packaging drums.