The work aims to develop a grafted antibacterial packaging and apply it to the preservation of aquatic products, so as to provide a new way for further application of grafted packaging films in production. First, polyhexamethylene biguanide hydrochloride (PHMB) and polyhexamethyleneguanidine hydrochloride (PHMG) were grafted onto starch. Then, they were subject to blending modification with polylactic acid (PLA) and poly (butylene adipate co-terephthalate) (PBAT) to prepare a grafted antibacterial packaging film by casting extrusion and apply the film to preservation of abalone. The antimicrobialization of starch was achieved by grafting PHMB and PHMG onto starch. The barrier property of the PLA/PBAT film with PHMB and PHMG was significantly improved (P＜0.05). It imparted bacteriostasis properties to the film, and delayed the increase of the total colonies, thiobarbituric acid and volatile base nitrogen in abalone. The grafting of PHMB and PHMG onto starch effectively improves the barrier property of the film. The starch-g-PHMB/PLA/PBAT and starch-g-PHMG/PLA/PBAT films can effectively inhabit the microbial action, delay the oxidation and spoilage of abalone and effectively extend the shelf life of abalone.