The work aims to review the research status and application progress of metal-organic frameworks (MOFs) as carrier systems in the field of food antibacterial packaging, so as to provide reference for the development and application of MOFs antibacterial packaging materials. Firstly, the basic concepts and classification of MOFs were introduced. Secondly, the preparation methods of MOFs (heating method, mechanical method and electrochemical method) were analyzed. Then, the applications of MOFs as carrier systems in the fields of inorganic antibacterial agents, organic antibacterial agents and natural antibacterial agents in recent years were summarized. Finally, the opportunities and challenges of MOFs as carrier systems were discussed. In general, as a porous composite material combining organic and inorganic materials, MOFs can not only effectively encapsulate antibacterial agents to achieve sustained release and controlled release, but also improve their antibacterial properties, mechanical properties and UV resistance when used as polymer fillers. Therefore, MOFs have great potential in the preparation of efficient and safe food antibacterial packaging.