The work aims to study the migration behavior of 15 primary aromatic amines (PAAs) in biodegradable tableware. Four different food simulant solutions were prepared for migration experiments. Qualitative and quantitative analyses were performed based on ultrahigh-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) to detect the migration of PAAs from biodegradable tableware to different food matrices. The total run time of UPLC-MS/MS was 12 min, and 15 PAAs could be separated within 7 min. The LODs and LOQs of different PAAs were between 0.2-3.0 μg/kg and 0.5-9.9 μg/kg, respectively, which met the requirement of legislation (10 μg/kg). The migration concentrations of most of PAAs migrated from the biode-gradable tableware to different food matrices were smaller than the required concentration except for the 1,5-diaminonaphthalene and 2,4-dimethylaniline. The PAAs in biodegradable tableware can migrate to food matrices during the usage, which is potentially harmful to consumers. The established method provides scientific support for reducing food safety risks by detecting PAAs migration amount in biodegradable tableware.