The work aims to replace PE plastic wraps with fully biodegradable PLA/PBAT/ESO composite films and apply them in fruit preservation packaging. The moisture permeability, air permeability and mechanical properties of commercial PE films and laboratory-made PLA/PBAT/ESO composite films were measured. With fresh strawberries as the preservation objects and unpackaged strawberries as the blank control, the preservation effects of PE plastic wraps and degradable PLA/PBAT/ESO films on strawberries were studied at 4 ℃. The results showed that compared with PE plastic wraps, fully degradable PLA/PBAT/ESO films had better preservation effect, moisture permeability, air permeability and mechanical properties. It could effectively inhibit the decline of soluble solids, hardness, titratable acid and vitamin C content of fruits and maintain the taste, flavor and nutrients of strawberries during storage. Due to the higher air and moisture permeability, PLA/PBAT/ESO films can reduce the condensation phenomenon and the growth of microorganisms, which effectively delay the deterioration of moisture sensitive fruit products such as strawberries and maintain the storage quality of fruits.