The work aims to analyze the structural strength of filter assembler spreader and optimize its design to ensure the safety of large industrial machinery in assembly, packaging, lifting and transfer. Foot weighing test was designed to obtain the weight of filter assembler by the weighing sensor and determine the load of the spreader. The finite element analysis model of the cigarette filter assembler spreader was established. Under the quasi-static state, the stress-strain distribution of the spreader was discussed with a partial load coefficient of 1.5. Then, the spreader structure was optimized based on the maximum structural stress and allowable safety factors. The maximum stress of the bottom plate was 79.6 MPa, and the safety factor was greater than 3. The maximum stress of the lifting member was 47.6 MPa, and the safety factor exceeded 5. Besides, the maximum stress of the optimized brace parts was 175 MPa, and the safety factor was greater than 1.3. Finally, the lifting test was carried out to the filter assembler spreader. According to the test results, the designed spreader could lift and transfer the filter assembler safely. The test results were consistent with the simulation results. The designed and optimized spreader structure meets the strength requirements and can lift, package and transfer the filter assembler safely. The research provides an important theoretical basis for the safety design of industrial machinery system in package and transfer.