The work aims to study the method for monitoring and evaluating the fluctuation and consistency of volatile and semi-volatile organic compounds (VOCs and SVOCs) in label paper and printing material for cigarette. Headspace-gas chromatography/mass spectrometry (HS-GC/MS) was used to collect the chromatograms of VOCs and SVOCs in package printed matters and raw materials of cigarette. The calibrated chromatograms were obtained after calibrating the retention time at different signal acquisition time periods with double internal standards of benzene-d6 and naphthalene-d8. Based on the calibration chromatograms, the quality control charts were constructed for monitoring and evaluating the fluctuation/consistency of VOCs and SVOCs in packaging material for cigarette. The developed method was simple in operation and good reproducibility. It exhibited good performance in correcting the retention time shift caused by changing the chromatographic column, switching the instrument and other instrument performance fluctuations. The minimum correlation coefficient between the spectra increased from 0.4076 to 0.9629. With this method, the overall differences of such compounds in different manufacturers and packaging papers could be identified efficiently (P<0.05), and the mean difference rates of the correlation coefficients were 12.5% and 38.6%, respectively. This study provided a method for signal acquisition, spectral correction and quality control of VOCs and SVOCs in packaging material for cigarette, which indicated that it could be served as a useful means for evaluating the quality stability of packaging paper and printing material.