Research Progress of Common Packaging Materials and Containers of Oral Solid Preparations

WANG Bo-yang, WANG Min, CHU Cang, ZHAO Yan-zhong

Packaging Engineering ›› 2023 ›› Issue (3) : 87-95.

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PDF(658 KB)
Packaging Engineering ›› 2023 ›› Issue (3) : 87-95. DOI: 10.19554/j.cnki.1001-3563.2023.03.011

Research Progress of Common Packaging Materials and Containers of Oral Solid Preparations

  • WANG Bo-yang, WANG Min, CHU Cang, ZHAO Yan-zhong
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Abstract

The work aims to provide theoretical reference and practical basis for accurately choosing the suitable packaging containers for different oral solid preparations.Based on the characteristics of raw materials and auxiliary materials in the commonly used packaging containers of oral solid preparations, the characteristics and research and application progress of different packaging containers for oral solid preparations were reviewed by analyzing the technical requirements of different packaging containers, and introducing the domestic review system of pharmaceutical packaging materials and the current registration information of pharmaceutical packaging materials in the Center for Drug Evaluation, NMPA. For preparations with precise dose requirements or small daily dose, the single-dose individually packaged blister packs should be chosen. For drugs requiring long-term medication or drugs with large daily dose, the pharmaceutical plastic bottles should be chosen. The pharmaceutical laminated films and pouches were mostly used for granules and powders. For aromatic, greasy, volatile and oxidizable drugs with larger packaging specifications but not suitable for storage in plastic bottles, glass bottles should be chosen. The drug manufacturers should comprehensively consider the physicochemical properties of packaging raw materials, compatibility with packaged drugs, mechanical properties, content, convenience in carrying and use, and price-cost when choosing drug packaging, and choose the appropriate packaging container to ensure the stability, safety and effectivity of drugs.

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WANG Bo-yang, WANG Min, CHU Cang, ZHAO Yan-zhong. Research Progress of Common Packaging Materials and Containers of Oral Solid Preparations[J]. Packaging Engineering. 2023(3): 87-95 https://doi.org/10.19554/j.cnki.1001-3563.2023.03.011
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