The work aims to briefly introduce, classify and summarize the synthesis methods of metal organic frames (MOFs) and their application in food packaging, to provide views for design and preparation of functional food packages based on MOFs, so as to promote the practical application of MOFs in food packaging. Firstly, synthesis methods of MOFs, including co-precipitation, diffusion, solvothermal and microwave synthesis methods were summarized. Then, the applications of MOFs or their composites in antibacterial agent, preservation, ripening and detection were systemically analyzed. Finally, the challenges and opportunities of MOFs in the application of food packaging were also discussed. In general, the composition and structure of MOFs can be artificially designed and adjusted to obtain rich physicochemical properties, so as to achieve specific functions of food preservation. Therefore, MOFs have high application values and industrial prospects in functional and intelligent food packaging.