The work aims to explore the preservation effects of BioSuee film on postharvest quality of fresh grape and the degradation property of the film during storage, and screen out BioSuee film of good preservation and degradation effects. Thompson seedless grapes of Xinjiang were packed with BioSuee films (B4, B5, B6) and PE film, and stored at (15±1) oC for 14 days. All kinds of films were placed in natural condition and soil for 140 days for observation. By analyzing physiological quality of grapes, gas composition in packaging film and degradation of packaging film, the effects of BioSuee film on grape storage quality and its degradation were discussed. The postharvest quality of grape could be maintained well by all BioSuee films. The degradation rates of B4, B5 and B6 packaging film groups were 84.7%, 81.22% and 92.8%, respectively. At the end of storage, the weight loss rate and decay rate of B6 film group were 7.62% and 8.8%, respectively, which were only 75.37% and 28.33% of PE storage group. The soluble solid content and hardness of the Thompson seedless grape were 18.8% and 4.94 N, which were 20.44% and 10.46% higher than those of PE storage group, respectively. In the middle and late period, the CO2 content (volume fraction) of grade packaged with B6 film remained in the range of 3.5%-4%, and the O2 content (volume fraction) fluctuated in the range of 16.6%-16.7%. At the end of degradation, the weight loss rate and elongation at break of B6 film in soil were 12.64% and 6.84%, respectively. The surface of B6 film was obviously broken and cracked from the observation of morphology and microstructure studies. Compared with other treatment groups, B6 film can better maintain the storage quality of Thompson seedless grape and has more excellent degradation effect.