The paper aims to propose a novel design strategy to enhance the electrostrictive property of Na0.5Bi0.5TiO3-based materials by inducing defects, which can be used in ink-jet printing of packaging materials. 0.7 (Bi0.5Na0.5) Ti0.9Mn0.1O3-0.3Sr(1-3x/2)Bix□x/2TiO3 (NBT-SBxT-Mn) ceramics were prepared using a conventional solid-state reaction method. The local defects could be created by VA and VO in the ceramics though modifying with Sr(1-3x/2)Bix□x/2TiO3, leaving a "non-polar" phase with PNRs at zero electric field. Meanwhile, defect dipoles originated from Mn and VO were induced into the ceramics by doping MnO, resulting in high electrostrictive strain with ultra-low hysteresis. All the samples exhibited both nonpolar phase structure with PNRs and typical features of relaxor characteristics with γ>1.80. With the increasing doping content x, the oxygen vacancy concentration decreased firstly and then had an obvious increase. The decrease of VO concentration reflects the increase of defect dipole formation in NBT-SBxT-Mn ceramics. Accordingly, high electrostrictive coefficients Q33=0.036 m4/C2 were achieved for the composition of x=0.07 due to the combined contribution of VA-VO local defects, Mn-VO defect dipoles, the relaxor characteristics and the formed PNRs. These results provide some instructive thought to further enhance the electro-strictive property of NBT-based materials by inducing defects