The modified polyester coating is prepared to solve the problems of poor adhesion and shrinkage between the pure polyester coating and the substrate due to poor wettability, so as to obtain a new coating material for tinplate food packaging with excellent comprehensive performance. In this work, diacid and dialcohol were used as raw materials to synthesize polyester resin through the condensation polymerization method. Then the bisphenol F epoxy resin was used to modify the synthesis of polyester to prepare epoxy modified polyester resin, which was then cured with amine silane as the curing agent. The performance differences between silylated epoxy modified polyester resin coatings and epoxy modified polyester coatings cured with conventional amino resin were characterized by GPC, FTIR, TGA, OM, WCA and adhesion analysis. Through performance comparison, it is found that the dosage ratio of silane curing agent is 3∶1, mEster 1.0 and mEster 1.1 have the best performance. The coatings have good wettability on the tinplate substrate, less shrinkage cavity or other defects, good water boiling resistance, good pencil hardness of 2H, and the surface is still intact after wiped with acetone for 50 times. Meanwhile, the decomposition temperature is above 250 ℃. The silylated epoxy modified polyester coatings contains Si−O−Si bond, which is conductive to the excellent performance of the coatings. The coatings can be applied in food packaging materials of tinplate or other metal substrates.