The work aims to analyze the multi-color overprinting process of a cigarette mark product and propose a new process and technical scheme to remove the overprinting silver edge in view of the demand for multi-color high-precision overprinting on laser column card paper as substrate and the needs of traditional production process to reserve 10-15 mm silver edge for background color and alignment color-mark printing, so as to reduce the manufacturing cost. The product structure and the principle of gravure automatic overprinting system were analyzed. The overprinting process of gravure printing was designed and optimized. The waste area of product die-cutting was used to print the background color and alignment color-mark, in order to ensure that the alignment color-mark printed at the die-cutting position met the overprinting requirements, determine the best position of the background color block and alignment mark in the product layout, formulate the printing color group matching the product color sequence with the gravure printing unit and prevent the background color from conflicting with the subsequent alignment mark. Then, the alignment basis was provided for the next group of alignment marks by covering or hollowing-out treatment. The gravure printing and overprinting process of a cigarette mark product was optimized. The waste area of die-cutting was used to print the background color and the alignment mark, which met the requirements of high-speed and high-precision multi-color gravure overprinting, and achieve a reduction of 2% of laser column card paper in the same products. At the same time, the usage of the 1# color sequence ink was reduced by about 33.33%. Through the analysis on automatic overprinting system and the design and optimization of overprinting process, it is proved that the technical scheme of removing overprinting silver edge is feasible. 10-15 mm silver edge of laser column card paper can be eliminated in actual production, and the utilization rate of laser column card paper is improved.