In order to improve the weighing accuracy and efficiency of food packaging process measurement components, an intelligent control algorithm is used to design a high-precision measurement control system. Based on the analysis of the working principle of the dynamic weighing system, a mathematical model of the weighing process is established, and the control object is converted from the opening of the discharge valve to the position of the motor shaft. Considering the defects of traditional PID control, a high precision measurement control system is designed by combining PI Ziegler-Nichols and predictive control. The control system can adjust the scale and integral coefficient on-line, and can restrain the parameter change and load disturbance. Predictive control can improve the convergence speed and tracking ability of the system. Finally, the simulation and experimental research are carried out. The simulation results show that the intelligent control algorithm has strong self-adaptive and self-tuning ability, and the measurement accuracy can reach the static weighing level, which is higher than 99.5%. Food packaging high precision measurement control system has the characteristics of high precision, good stability, high weighing efficiency, in the practical application of the weighing process control effect is relatively good.