This paper aims to introduce the research achievements in respiration metabolism way and control methods of post-harvest fruits and vegetables and provide theoretical basis for its physiology & biochemistry and preservationtechnology. This paper reviewed the effects of key pathways, enzymes, intermediates and preservation technologies onthe respiration metabolism way of post-harvest fruits and vegetables indomestic and foreign literatures, and it also summarized the mechanism of respiration metabolism of post-harvest fruits and vegetables and its effects regulated by preservation technology. By summarizing the production mechanism and regulation methods of key enzymes and intermediates in the respiratory metabolic pathway of post-harvest fruits and vegetables, this paper concluded that using preservation technology to control the respiratory metabolic pathway of post-harvest fruits and vegetables can reduce the respiratory metabolism. Respiratory metabolism as a main metabolic method of post-harvest fruits and vegetables, it can be regulated by physical, chemistry and biological preservation technology, which can significantly decrease the occurrence of browning, cold damage and quality degradation. It can be seen that the regulation of respiration metabolism will play an important role in the storage and sales of post-harvest fruits and vegetables.