The safety of biofilm formation on food contact surface by foodborne pathogenic bacteria and its control measures were reviewed in order to provide reference for solving the hazard problem of biofilm formation by foodborne pathogenic bacteria on food contact surface. The research summarized the hazards of foodborne pathogenic bacteria forming biofilm on food contact surface at domestically and worldwide about recent years, and mainly analyzed the biofilm formation mechanism, prevention and control measures and future development direction. Due to pathogenic bacteria formed biofilm structure with high adhesion, high resistance, wide adaptability and strong resistance on food contact surface. The conventional physical and chemical biofilm methods could not completely remove biofilm. Widespread microbial-derived antibiofilm agents, antimicrobial packaging materials and natural food chemical fungicides, with excellent characteristics of cracking, specificity, non-toxicity, environmental protection and antibacterial properties, have become effective resources for biofilmclearance control. Natural antimicrobial active substances, antibacterial packaging materials and bio-active antifungal membrane agents have gradually replaced the traditional physical and chemical biofilm removal methods, and becoming one of innovative way to effectively guarantee the food industry production and consumer food safety.