The work aims to study the migration of risk factors in the fruit and vegetable foam nets to make recommendations for the safety supervision of fruit and vegetable foam nets. The commercially available fruit and vegetable foam nets were used as the samples for screening fluorescent whitening agents and organic azo pigments. The risk factors screened out were used as the detection indexes of simulated migration experiments in 4% acetic acid, 95% ethanol, and isopropanol simulants. The screening experiments showed that the fruit and vegetable foam nets contained the fluorescent whitening agent 4, 4-bis (2-benzoxazolyl) stilbene (OB-1) while the organic azo pigment was not detected in the samples. In the migration experiments, the optical brightener OB-1 could migrate to 95% ethanol and isopropanol simulants.The findings suggest that the fluorescent whitening agent OB-1 in the foam nets of fruits and vegetables could migrate to non-acidic or oily substances, which might pose a potential threat to human health.