The paper aims to study the determination method of specific migration of 1-hexene in plastic products for food contact, to provide reference for the establishment of relevant testing standards and the detection and control of harmful substances. The effects of headspace equilibrium temperature, headspace equilibrium time, and chromatographic column on 1-hexene analysis were studied by immersion in different food simulants and analysis by headspace-gas chromatography. Under the optimized conditions, the target compounds can be separated and analyzed within 11 minutes through chromatographic column. The recoveries of 1-hexene at the addition levels of 0.5 mg/kg, 1.5 mg/kg and 3.0 mg/kg were 86.0%-105.3%, the RSD was 1.5%-4.4%(n=6), and the quantitative limit of the method was 0.1 mg/kg. This method is fast, accurate and sensitive, and is suitable for the determination of 1-hexene specific migration of food contact plastic products in different food simulants.