The work aims to study the effect and mechanism of ultrasonic wave on the making process of sea-slurry ice, and verify the feasibility of applying ultrasonic wave to the making process of sea-slurry ice. Experiments were carried out on the preparation of sea-slurry ice from seawater solution with specific salt concentration by ultrasonic wave with different power/frequency parameters. Applying specific parameters (power/frequency) to the seawater could accelerate the seawater crystallization, reduce the supercooling degree of 8.4 ℃, save the energy by 33.3%, shorten the preparation process time by 90.0 s, and refine the crystal size to 20.0 μm. In the experimental conditions of 33.0 kHz and 50.0 W, the effect of making sea-slurry ice was the best. The ultrasonic wave under appropriate conditions has the effect of promoting the making process of sea-slurry ice.