The work aims to understand the close relationship between the freshness of cultured large yellow croaker and the spoilage ability of specific spoilage organisms, to provide theoretical reference for the effective extension of shelf-life of large yellow croaker based on efficient bacteriostasis. The research progress of the preservation technology of large yellow croaker was summarized from physical, chemical and biological preservation. In view of that most kinds of preservation methods were realized by controlling spoilage organisms of fish, the species, spoilage potential and application value of specific spoilage organisms in large yellow croaker were described, and the influence of quorum sensing system on the spoilage potential of spoilage organisms was emphatically analyzed. Preservation technologies such as partial freezing and ice temperature were still limited in practical application due to their high requirements on equipment. The regulatory mechanism of quorum sensing of specific spoilage organisms in large yellow croaker was still unclear, and there were few types of natural quorum sensing inhibitors studied. The application of compound technology in the preservation of large yellow croaker has become a general trend, and it is the key to realize targeted bacteriostasis and optimize storage parameters to explore the spoilage mechanism of specific spoilage organisms targeted by quorum sensing.