The work aims to study the effect of biaxially oriented polypropylene plain (BOPP) film and polyethylene (PE) film on storage physicochemical indexes of grapes during cold storage, in order to provide a basis for prolonging the shelf life of grapes. As the experimental materials, the Ziqiu Vitis Daviaii grapes were packaged in 0.03 mm thick BOPP and PE films, respectively, each with a bunch of grapes, and stored in (0±0.5)℃ cold storage, with no packaging as the control. The preservation effects of different packaging materials at low storage temperature were studied by measuring the physiological and biochemical indexes every 10 days. The experimental results showed that, BOPP and PE packaging films could significantly reduce grape fruit dropping and weight loss, and slow down the rate of stem browning and the oxidation of vitamin C. The degradation of fruit's soluble solid and titratable acids could be delayed 30 days before storage. Compared with PE packaging, BOPP packaging could significantly reduce the occurrence of fruit decay and dropping, reduce the weight loss, and delay the decline of TSS and TA, anthocyanins and vitamin C content. BOPP packaging film has the best preservation effect, which can better maintain the appearance and nutrition quality of ZiqiuVitis Daviaii grape fruits, delay the senescence process, and extend their storage period.