The work aims to determine the best extraction technology of Polygonatum Polysaccharide by comparing the effects of different extraction technologies on the extraction rate of Polygonatum Polysaccharide. Water extraction and alcohol precipitation method and complex enzyme digestion method used to extract Polygonatum Polysaccharide were compared and analyzed. The optimal conditions of water extraction and alcohol precipitation were as follows: solid-liquid ratio of 1∶25 (g/mL), pH=6, temperature of 80 ℃, extraction time of 2 h and alcohol content of 70%, and the extraction rate of polysaccharide was 8.84% under the optimal conditions. The optimum combination of complex enzyme was cellulase: papain=3∶7, pH =5.0, enzymatic hydrolysis temperature of 50 ℃, solid-liquid ratio of 1∶20, content of enzyme of 5% and enzymolysis time of 2 h. Under the above conditions, the extraction rate of polysaccharide could reach 22%. The yield of polysaccharides by complex enzyme hydrolysis is much higher than that by ordinary water extraction and alcohol precipitation method. The experiment provides the optimal extraction technology of Polygonatum Polysaccharide and lays a rigorous theoretical foundation for the subsequent development of polysaccharides.