The work aims to study the effects of different preservation treatments of SO2 on the storage and safety of "Zuijinxiang" grape. The grapes were treated by SO2 gas+CT2 and SO2 gas+ simplified package as gaseous treatment combining solid preservative treatments and CK + CT2 and CK+simplified package as separate solid preservative treatments and then put in cold storage of (0±0.5)°C for 30, 60, 90 and 105 d, respectively. The fruit threshing rate, rot rate, respiration rate, ethylene production rate, soluble solids, titratable acid, Vc content, conductivity of stem and peel, MDA content, chlorophyll and anthocyanin, PPO and POD activities during the storage were analyzed. Among the four preservation treatments, CK+ simplified package treatment had a good effect on the inhibition of grape fruit rot, while SO2+ simplified package treatment had better inhibition on fruit dropping and could effectively maintain the soluble solid content, titratable acid content, Vc content and chlorophyll content of stem at the same time. Moreover, it could also inhibit the increase in the permeability of the stem and peel, and the content of malondialdehyde. It also played a positive role in reducing respiration and ethylene release, inhibiting browning, inhibiting PPO and POD activity. SO2 gas treatment combined with solid preservative treatment (SO2 gas + simplified package) can better maintain the grape quality during storage and delay the aging.