The work aims to verify that the Mu Yu Stone has beneficial effect on human body by studying the migration of calcium, iron and magnesium elements in food, with Mu Yu Stone as the food contact material. Samples were taken from the whole mining area, the Mu Yu Stone was ground into pieces, and the water-based and acidic food-simulating solvents were soaked. The migration of calcium, iron and magnesium elements was studied by atomic absorption spectrometer. The three main elements (i.e. calcium, iron and magnesium) in Changqing Mu Yu Stone in Shandong Province had different degrees of migration in water-based and acidic food-simulating solvents. Dolomite is the main constituent mineral of Changqing Mu Yu Stone in Shandong Province. Iron, calcium and magnesium can migrate from both the water-based food-simulating solvent (distilled water) soaking solution and acidic food-simulating solvent. The content of calcium, iron and magnesium in acidic food-simulating solvents (4% (volume fraction) acetic acid) is much higher than that in water-based food.