The work aims to improve the preservation properties of composite sustained released coatings on the storage quality of Sciaenops ocellatus fillets, and acquire efficient preserving material with long-acting effects. The tea polyphenol liposomes (TP-Lips) with sustained-release property and lysozyme (LZM) were mixed into chitosan (CS) solution to prepare TP-Lips/LZM-CS sustained released composite coating by tape casting method. The preservation properties of composite coatings were evaluated according to the freshness of fish fillets. TP-Lips/LZM-CS composite coating could inhibit the the microbial growth effectively, and delay the increase of pH and TBA value in the fish fillets, as well as the changes of texture. The antibacterial spectrum is broadened efficiently due to the combined use of TP, LZM and CS. Meanwhile, the slow-release system composed of liposomes and coating film makes the action time of TP and LZM longer, so the preservation properties of TP-Lips/LZM-CS composite coating is the optimal, and the shelf life of Sciaenops ocellatus fillets is extended to 15 days when they are refrigerated at 4 ℃.