The work aims to combine traditional woodblock watermark technology with modern science and technology, and reform the traditional technology through modern science and technology, so that the woodblock watermark can be inherited in another form. The regeneration of woodblock watermark in the digital background was researched based on the following three aspects: Firstly, the digital image processing technology was combined with the traditional woodblock watermark color separation steps. Secondly, the laser engraving technology was used to finish the printing process. Finally, the computer color matching technology was used to complete the final printing process. The experimental method was used to complete the woodblock watermark making process, and the anticipated effects were achieved. It is feasible to combine woodblock watermark with modern digital technology. The combination of modern science and technology and traditional technology is of positive significance to promote the development of woodblock watermark culture.