The work aims to establish a bisphenol A analysis method based on the high performance liquid chroma-tography to rapidly and accurately determine the bisphenol A content and its migration in 5 kinds of plastic packaging for PET bottled drinking water sold in Xiangyang. The pretreated sample was detected by high performance liquid chroma-tography-ultraviolet detection (HPLC-UV) with a column of ODS-C18 (4.6 mm×150.0 mm, 5 μm) at 30 ℃. The mobile phase was methanol-ammonium acetate (V∶V, 50∶50), and the flow rate was 1 mL/min. The detection wavelength was 280 nm. The limit of detection (LOD) of bisphenol A was 0.004 μg/mL, and the relative standard deviation (RSD) was 4.32% at the concentration of 0.02 μg/mL. When the linear concentration was within 0.01~200 μg/mL, the detection signal had a good linear correlation (r2＞0.9999) with bisphenol A concentration. The analysis capability of the method met the limited demand of national standard. Certain amount of Bisphenol A was found in the packaging of PET bottled drinking water of major brands sold in Xiangyang, while no bisphenol A was detected in drinking water. The recoveries of bisphenol A in PET packaging at the spiked concentration of 0.4, 4 and 40 μg/g were in the range of 70.30%~113.00%, and the recoveries of bisphenol A drinking water at the spiked concentration of 0.1, 1 and 10 μg/g were 90.00%~119.00%. The proposed method is simple, accurate and efficient, which is suitable for the analysis of bisphenol A content and its migration in the packaging of PET bottled drinking water.