The work aims to build a packaging box AR augmented reality application based on Android platform. With Unity3D software and Vuforia plug-in, the packaging box design picture was uploaded to the Database of Target Manager on Vuforia official website, so that AR camera in Vuforia plug-in could be used to recognize the packaging box design picture, and after recognition, the three-dimensional scene produced by 3DMAX software would be automatically superimposed in the lens of AR camera. It could realize various human-computer interaction functions of the three-dimensional scene. Finally, the Android SDK development environment well configured by Unity3D software could generate the App program of packaging box augmented reality based on Android platform. After the App application was installed on the mobile phone, the program would use the camera of the mobile phone. When the camera captured the packaging box, the virtual three-dimensional scene would be automatically superimposed on the packaging box, and be able to interact with the three-dimensional model. The program ran normally. The packaging design integrates three-dimensional image, sound, video and human-computer interaction by augmented reality technology. The packaging box not only has the traditional function, but also has the functions of enhancing product promotion, improving consumer experience and sublimating product awareness.