The work aims to develop and design a new type of transport packaging box suitable for supply chain packaging system. Firstly, online and offline researches were conducted to understand the basic information and issues of existing transport packaging boxes in supply chain packaging system. Secondly, based on the research results, new transport packaging boxes were developed to replace the existing ones. At the same time, the economic benefit was estimated based on the simulation test. The performance of the transport packaging box was superior to the existing one in terms of environmental protection, operational efficiency and cost. This kind of transport packaging box is a sharing and environmental friendly transport packaging box suitable for fast retailing industry. It has such advantages as low price, ease to use, energy saving and environmental protection, and rich function. Its excellent comprehensive indices, strong operability and high cost performance signify that this new type of packaging box has highly promising market prospect and it is an inevitable product of the era of intelligent logistics.