The work aims to introduce principle, characteristics and its research and application progress of stereo imaging technology of lenticular sheet. The research status and application progress of the micro-structure design of lenticular sheet, the extrusion technology of PET lenticular sheet and design and fabrication of “Magic 3D” software in the stereo imaging technology of lenticular sheet were reviewed. The classification and fabrication methods of stereo imaging technology of lenticular sheet were emphatically expounded, and its application in the packaging was described. In recent years, a lot of research results have been achieved in the stereo imaging technology of lenticular sheet, which promote the rapid industrial development of wine and food packaging. Good encryption processing of lenticular sheet makes the plane image produce stereo sense, and the quality safety of the packaged products is effectively controlled. The stereo imaging technology of lenticular sheet is widely applied in wine and food packaging and other fields, and it is also one of the development directions of electronic packaging, pharmaceutical packaging and advertising industry in the future.