The work aims to develop a fragility measurement scheme easy to operate for the cushioning packaging design and analysis of apples, with the apples as study object. The elastic stiffness of apples was determined by the static compression test. The critical drop height of damage was obtained by the drop test. Furthermore, the fragility of apples was calculated on the basis of single freedom theoretical model. Then, an optimal packaging scheme was designed according to the apple fragility and static cushioning coefficient of the cushioning materials. Finally, the road random vibration test and drop test were simulated to evaluate the feasibility of the above-mentioned cushioning scheme. For apples with mesh-foam protection, the critical drop height of damage was 5 cm, the elastic stiffness was 106.59 kN/m, and the natural frequency was 109.79 Hz, while those without mesh-foam protection were 10 cm, 104.48 kN/m and 106.58 Hz, respectively, and the fragility Gc was about 96. In view of the above, as for the design according to the 80 cm handling drop height, the cushioning material EPE should be 1.98 cm thick. The fragility measurement scheme developed has high precision and it has such advantages as low demand on the instruments, good handle ability and generalization, compared with the traditional fragility measurement method. It is easy to apply the fragility measurement scheme in the fragility measurement of other types of packages.