The work aims to propose a cam mechanism simulation design based on three kinds of software (Matlab, ADAMS and SolidWorks) combined with the complicated motion law of roller putter, in order to reduce the design difficulty and shorten the development period. The motion data of the putter were outputted by Matlab programming. Based on the cam simulation toolbox in ADAMS software, the cam model of theoretical profile was obtained. In Solidworks software, the cam 3D model of actual profile was generated based on the cam model of theoretical profile. Based on three kinds of software, the actual profile curves of roller putter cam mechanism were finally obtained. The research shows that the 3D modeling of cam mechanism of complicated motion law of the roller putter based on three kinds of software (ADAMS, MATLAB and Solidworks) provides an efficient general method for designing cam mechanism, and has certain promotion and application value.