The work aims to develop a high-performance anti-static corrugated board and carton, and study the effect of coating amount and temperature, relative humidity and mechanical friction of transport environment on its anti-static performance. The anti-static coating was uniformly coated on the surface of the base paper by means of quantitative coating. The relationship between the anti-static coating and the anti-static level of the paperboard was studied by changing the coating amount. The temperature, relative humidity and friction parameters (times and intensities) of the environment were changed for the simulation study on the effect of temperature, relative humidity and friction parameters (caused by mechanical force such as vibration and impact) on the anti-static performance of the corrugated carton during actual transportation. Within the scope of study, as the temperature and relative humidity increased, the surface resistivity of the anti-static corrugated board also increased, but the anti-static level did not change, and it was still an electrostatically conductive material, in which the relative humidity had a greater effect on the antistatic effect than the temperature. The friction had a greater effect on anti-static performance than relative humidity and temperature. Temperature, relative humidity and friction have different effects on the anti-static performance of corrugated board. However, the board is still the electrostatically protected material and can effectively protect the contents from electrostatic hazards.