The work aims to establish an assessment method and select photoinitiators and monomers with low viscosity suitable for UV-LED curable inkjet inks. UV-visible absorption spectra of six common photoinitiators such as TPO, ITX, DETX, 819, 784 and TPO-L were characterized by UV-Vis spectrophotometer. TPO was taken as initiator. Binders and inks for UV-LED inkjet inks were prepared with five commonly used low-viscosity monomers such as HDDA, ACMO, DPGDA, EOEOEA and DMAA. The curing speed of the binders and the color of the cured films were characterized by infrared spectroscopy and visible light transmission spectroscopy, and the degree of dryness was determined by acupressure method. The binder containing DMAA, EOEOEA had poor film-forming property. The binder containing ACMO had better transparency. The established evaluation method is reasonable and effective to meet the safety of food and drug packaging. The photoinitiators that can be used for UV-LED curing are TPO, TPO-L and 819; based on low viscosity and degree of curing, the five monomers are suitable for inkjet ink formulation from high to low order: DPGDA, HDDA, ACMO, EOEOEA, DMAA.